To spark your curiosity, here’s a list of some of the rarest diseases in the world. Hopefully, if you’re lucky, you’ll go your entire life without having to deal with one of these conditions up close and personal. Check it out and see if any of your obscure symptoms match a syndrome listed.

Plenty of people are afraid of things like spiders, lightning, and enclosed spaces, but did you know there’s a phobia for just about anything and everything you can think of? Here are 50 of the most bizarre fears that have actually been formally diagnosed.