Understanding PrEP and PEP for HIV Prevention

3 minute read

By Hilary Valdez

Pre-exposure prophylaxis (PrEP) and post-exposure prophylaxis (PEP) are pivotal strategies in preventing HIV transmission for those at high risk. With FDA-approved medications and structured follow-up protocols, these methods offer significant risk reduction when adhered to properly. Exploring both the nuances of PrEP and PEP will empower individuals with the knowledge needed to effectively manage and minimize HIV exposure risks.

Understanding Pre-Exposure Prophylaxis (PrEP)

Pre-exposure prophylaxis, commonly known as PrEP, is a proactive HIV prevention method designed for individuals who are HIV negative but are at high risk of exposure to the virus. It significantly reduces the risk of acquiring HIV when taken consistently as prescribed. The U.S. FDA has approved three medications for PrEP: Truvada, Descovy, and Apretude. Truvada and Descovy are oral medications taken daily, while Apretude is a long-acting injectable taken every two months. To maintain effectiveness, these medications must be taken consistently. PrEP does not provide protection against other sexually transmitted infections (STIs), so it should be combined with condoms for broader protection during sexual activities ensuring a comprehensive prevention approach.

The Centers for Disease Control and Prevention (CDC) recommends PrEP for individuals who are HIV negative and have had anal or vaginal sex in the past six months, meeting certain risk criteria such as having a partner with HIV, inconsistent condom use, or a recent STI diagnosis. It is also advised for those who inject drugs and share drug paraphernalia. Studies indicate that consistent PrEP usage reduces HIV risk from sex by about 99% and from injection drug use by at least 74%. However, Apretude is currently not recommended for people who inject drugs or women involved in receptive vaginal sex due to a lack of evaluated effectiveness effective strategies tailored to individual cases.

Post-Exposure Prophylaxis (PEP) as an Emergency Measure

Post-Exposure Prophylaxis (PEP) involves a 28-day course of HIV medicines initiated after potential exposure to prevent HIV infection. However, it must begin within 72 hours after exposure. PEP is only for emergencies and is not a substitute for regular prevention methods like PrEP or consistent condom use. PEP may be considered for individuals possibly exposed to HIV through recent sexual contact, needle sharing, sexual assault, or occupational hazards particularly within a critical timeframe.

While PEP can be over 80% effective if taken correctly for the complete 28 days, it is not as reliable as PrEP and should be complemented with other preventive measures. After completing PEP, individuals testing negative for HIV are encouraged to adopt preventive measures like PrEP and consistent condom use. Those testing positive should seek further testing and HIV treatment options to ensure the best possible care moving forward monitoring and subsequent care recommendations.

Regular Monitoring, Side Effects, and Access to PrEP

Regular follow-ups, including an HIV test every three months, are necessary when on PrEP. Consistent daily dosing for oral PrEP and adherence to injection schedules for Apretude are critical for maintaining HIV prevention efficacy. Some mild side effects of PrEP can include nausea, diarrhea, headache, and dizziness, but they typically resolve over time. Any concerning or persistent side effects should be discussed with a healthcare provider to ensure safety and efficacy appropriate monitoring steps.

PrEP is available to anyone who requests it, emphasizing an inclusive approach to prevention, regardless of whether they report traditional HIV risk factors. Various options exist to accommodate different preferences and medical conditions, such as daily pills and bi-monthly injections. It’s also crucial for individuals considering PrEP to consult healthcare providers to determine their suitability and ensure that any existing medical conditions, like renal function concerns, are managed effectively. Access is supported by insurance and assistance programs, making it more affordable and available without cost-sharing, which enhances its reach and utility as a preventative measure ensuring widespread availability.

Why You Should Learn More About HIV Treatment and Prevention Today

Understanding the options for HIV prevention and treatment is paramount for individuals at risk of exposure. With advances like PrEP and PEP, people can significantly reduce their risk of HIV transmission by using these strategies as part of a comprehensive prevention plan. Education and awareness are vital components of these strategies, helping to reduce stigma and empower at-risk communities to take charge of their health. By staying informed about the availability of medications, side effects, and ongoing testing requirements, individuals are better equipped to make informed decisions about their health and well-being.

Sources

Pre-exposure Prophylaxis in Detail

Post-Exposure Prophylaxis Information

Guidelines for HIV Prevention

Comprehensive Guide on PrEP Usage

Global Perspectives on PrEP

Contributor

Hilary Valdez is a dedicated health writer at Healthversed, with a passion for empowering readers to take control of their well-being. She specializes in exploring topics like preventative care, mental health, and lifestyle habits that promote a balanced life. Outside of writing, she enjoys nature walks, mindfulness practices, and discovering new superfoods to incorporate into her daily routine.