VEGFR2 antibodies are essential in unraveling vascular development and related diseases. Key options like DC101 and VEGFR2/KDR Antibody 26415-1-AP offer researchers diverse applications and high reliability through rigorous validation. Understanding their formats, storage, and handling enhances experimental success, enabling significant contributions to medical research and therapeutic advancements in areas such as diabetic retinopathy and Parkinson’s Disease.
Understanding VEGFR2 Antibodies
VEGFR2 antibodies are pivotal tools in scientific research aimed at understanding the mechanisms of vascular development and related diseases. VEGFR2, or Vascular Endothelial Growth Factor Receptor 2, plays a critical role as the primary mediator of vascular endothelial growth factor (VEGF)-induced processes, such as endothelial cell proliferation and angiogenesis. Among the various options, the DC101 monoclonal antibody is notable for its potential to inhibit VEGFR2 signaling both in vitro and in vivo, making it an invaluable resource for research where VEGFR-2 is implicated.
Formats and Applications
The availability of VEGFR2 antibodies in multiple formats allows for flexibility in research applications. For example, the VEGFR2/KDR Antibody 26415-1-AP is versatile, suitable for an array of experiments such as Western Blot, Immunohistochemistry, and immunofluorescence. Moreover, its application ranges across various species including human, mouse, and rat samples, facilitating diverse studies in vascular and angiogenesis research. Similarly, the VEGFR2 antibody LS-C692334, conjugated with FITC, is designed specifically for human proteins and aids in Western blot applications by ensuring complete immunogen sequence identity and high specificity.
Validation and Quality Assurance
The integrity and effectiveness of an antibody is contingent upon rigorous validation and quality control measures. The DC101 antibody, for instance, is noted for its high purity of over 95% and ultra-low endotoxin levels, making it highly reliable in experimental research. It undergoes advanced validation processes such as murine pathogen screening, ensuring that it meets the necessary standards for accurate biological investigations. These validations enhance the antibody’s reliability, ensuring the replicability of results.
Storage and Handling Considerations
Proper storage and handling are crucial in maintaining the stability and functionality of VEGFR2 antibodies. The VEGFR2/KDR Antibody 26415-1-AP’s stability is guaranteed for one year when stored at -20°C, without the need for aliquoting, which simplifies its handling for long-term use. Similarly, the VEGFR2 antibody LS-C692334 should be kept aliquoted at -20°C for up to 12 months to maintain its integrity, avoiding repeated freeze/thaw cycles that could degrade its performance. Adhering to storage guidelines enhances the reliability of experimental results.
Practical Applications and Research Impact
The wide applicability of VEGFR2 antibodies extends into several domains of medical and biological research. For instance, the VEGFR2/KDR Antibody 26415-1-AP has been instrumental in studies related to diabetic skin wounds, regeneration of sweat glands, and potential therapeutic interventions for diabetic retinopathy. It also demonstrates potential therapeutic applications in Parkinson’s Disease, owing to its role in enhancing angiogenesis. Such breakthroughs underscore the importance of selecting the appropriate antibody for specific research needs, optimizing their impact on scientific discovery.
Why You Should Learn More About VEGFR2 Antibodies Today
Investing in the right VEGFR2 antibody requires understanding their formats, applications, and validation processes. The top-tier quality and versatility of options like the DC101 and VEGFR2/KDR Antibody 26415-1-AP make them indispensable in vascular and angiogenesis research. Proper handling and storage further ensure experimental efficacy. By staying informed about the latest developments in antibody technology and application, researchers can continue to advance their work in uncovering the intricacies of VEGFR2 pathways and their roles in health and disease. Discover the scope of these antibodies and their significant contribution to innovative research and therapeutic developments.