New Medications for Tardive Dyskinesia Treatment

2 minute read

By Victoria Hamilton

Tardive dyskinesia (TD), a movement disorder triggered by prolonged antipsychotic use, affects thousands across the United States. Understanding its impact, innovative treatments, and management strategies is crucial for improving patient quality of life. Dive into the role of healthcare providers, emerging medications like Austedo XR, and other therapeutic advancements that can transform patient care and well-being.

Understanding Tardive Dyskinesia and Its Impact

Tardive dyskinesia (TD) is a movement disorder characterized by involuntary, repetitive body movements. It often results from the long-term use of antipsychotic medications, especially those that block dopamine receptors. These movements can impact various parts of the body, including facial muscles, neck, arms, and legs and range from mild to severe forms, affecting routine activities and quality of life.

Common Treatments for Tardive Dyskinesia

The American Academy of Neurology has recommended several treatment options for TD, including clonazepam and ginkgo biloba. Clonazepam, in particular, has shown a 35% reduction in symptoms. Moreover, FDA-approved medications like valbenazine and deutetrabenazine, both VMAT2 inhibitors, have demonstrated significant improvements in TD symptoms. In clinical trials such as the KINECT 3, valbenazine significantly reduced AIMS scores displaying its efficacy.

Austedo XR: A New Approved Medication

Recent advancements include the approval of Austedo XR, a once-daily pill for TD and Huntington’s chorea treatment. By offering multiple strengths (30, 36, 42, 48 mg), Austedo XR provides convenience, as effects are visible within two weeks. Its long-term safety over three years makes it a preferred choice for patients.

Additional Therapeutic Strategies

Other therapeutic approaches for managing TD symptoms include atypical antipsychotics like clozapine and risperidone, which lower the risk compared to traditional neuroleptics. Adjustments in medication, dosage changes, and discontinuation when feasible play crucial roles in managing TD effectively. Alternative treatments like vitamin E, benzodiazepines, botulinum toxin, and dopamine-depleting agents also show positive outcomes for some patients. Routine screenings every three to six months ensure early detection and management.

Role of Healthcare Providers

Healthcare providers are critical in diagnosing and treating TD. Diagnosis often involves the use of scales such as the Abnormal Involuntary Movement Scale (AIMS). Physicians suggest working with specialists, including neurologists and psychiatrists, to accurately identify and manage TD, potentially using consultative measures like deep-brain stimulation for severe cases. Their guidance in monitoring treatments and self-care strategies is vital for patients.

Why You Should Learn More About Tardive Dyskinesia Today

Tardive dyskinesia is a prevalent condition, affecting nearly 500,000 people in the United States. Understanding available treatments and management strategies is essential for those affected by this disorder, primarily those treated for mental health conditions like schizophrenia, schizoaffective disorder, or bipolar disorder who are at higher risk. By exploring the latest medical advancements, such as Austedo XR and other effective medications, individuals can better manage their symptoms and improve their quality of life. As research progresses, staying informed on the latest developments in TD treatment enhances clinical outcomes for patients.

Sources

Austedo XR Approved for TD

Management of Tardive Dyskinesia

Cleveland Clinic on TD

Contributor

Victoria Hamilton is a health and wellness writer dedicated to making well-being accessible to everyone. With a passion for evidence-based research and a talent for breaking down complex topics, she provides readers with practical insights on nutrition, fitness, mental health, and overall self-care. When she’s not writing, Victoria enjoys practicing meditation, experimenting with healthy recipes, and exploring the great outdoors.