Exploring Upcoming Diabetes Clinical Trials in February 2026

3 minute read

By Victoria Hamilton

February 2026 heralds a transformative period in diabetes research, with groundbreaking clinical trials set to explore innovative treatments for both Type 1 and Type 2 diabetes. From novel compounds and gene therapies to combination treatments, these trials promise to advance diabetes management significantly. Discover the potential breakthroughs that could redefine care for millions worldwide.

Exploring Upcoming Diabetes Clinical Trials in February 2026

Diabetes remains a significant global health challenge, with millions affected by both Type 1 and Type 2 diabetes. As researchers continue to seek innovative treatments, clinical trials play a crucial role in advancing medical knowledge and developing new therapies. February 2026 promises to be a pivotal month for diabetes research, with several noteworthy clinical trials on the horizon. These trials aim to explore new compounds, gene therapies, and combination treatments that could potentially transform diabetes management.

New Compound Trials for Type 1 Diabetes

One of the upcoming trials focuses on a novel compound designed to treat Type 1 diabetes. This trial aims to understand the compound’s absorption, transportation, and elimination in the body. Participants will receive subcutaneous injections, and the trial will be conducted in two parts, each requiring a stay at a research facility in Groningen. The trial is open to healthy males and females aged 18 to 65, with a BMI between 25 and 45 kg/m2. Participants will be compensated for their involvement, and travel expenses will be reimbursed (source).

Advancements in Diabetes Gene Therapy

Genprex, Inc. is making strides in its diabetes gene therapy program with its GPX-002 drug candidate. This therapy targets both Type 1 and Type 2 diabetes, showing promising results in preclinical studies. The company has successfully transferred the production of GPX-002 to a Contract Development and Manufacturing Organization (CDMO), a critical step in preparing for human clinical trials. Genprex plans to engage with the U.S. Food and Drug Administration (FDA) to discuss IND-enabling preclinical studies, marking a significant milestone in the development of this innovative therapy (source).

Combination Therapy for Type 2 Diabetes

Another important trial set for February 2026 is a randomized, multicenter study evaluating the efficacy, safety, and tolerability of a fixed-dose combination of Dapagliflozin and Gliclazide. This trial targets patients with Type 2 Diabetes Mellitus who have not achieved adequate glycemic control with Metformin monotherapy. The study aims to determine whether the combination therapy offers superior glycemic control compared to Dapagliflozin alone. The trial’s design includes multiple centers, enhancing the generalizability of the findings across diverse patient populations and healthcare settings (source).

Why You Should Learn More About Diabetes Clinical Trials Today

As February 2026 approaches, the landscape of diabetes treatment is poised for significant advancements. The upcoming clinical trials offer hope for new therapies that could improve the lives of those living with diabetes. By exploring innovative compounds, gene therapies, and combination treatments, researchers are paving the way for more effective and personalized diabetes management strategies. Staying informed about these developments is crucial for patients, healthcare providers, and researchers alike, as they hold the potential to reshape the future of diabetes care.

Contributor

Victoria Hamilton is a health and wellness writer dedicated to making well-being accessible to everyone. With a passion for evidence-based research and a talent for breaking down complex topics, she provides readers with practical insights on nutrition, fitness, mental health, and overall self-care. When she’s not writing, Victoria enjoys practicing meditation, experimenting with healthy recipes, and exploring the great outdoors.